Nuclear Nephrology Division

Radionuclide Renal Scintigraphy provides important anatomical and functional information to assist in the diagnosis and management of patients with a variety of suspected genito-urinary problems. The available tests at NINMAS are:
• Functional Renal Imaging or DTPA Renogram is performed to look at the blood supply, function and excretion of urine from the kidneys.

• DTPA Renogram with diuretic challenge is done to distinguish between obstructive hydronephrosis and non-obstructive collecting system dilatation attributable to vesicoureteric reflux, urinary tract infection, congenital malformation, previous obstruction or a noncompliant bladder.

• Captopril Renogram is done to diagnose renovascular hypertension which accounts for 1-4% of all cases of hypertension.

• Renal Cortical imaging/ DMSA Planar & SPECT Scintigraphy for the detection of cortical scarring associated with acute or chronic pyelonephritis, especially in children. It can also be done for the evaluation of space-occupying lesion, functioning pseudotumor such as cortical Columns of Bertin, or edema.

• Quantitation of Renal Function. It is an important part of nuclear nephrology as up to half of the renal function, including GFR may be lost before serum creatinine levels become abnormal. Direct measurement of GFR by using radiopharmaceuticals plays an important role in the early assessment of renal function. GFR are estimated in two ways

o DTPA Renogram and GFR

o Estimation of GFR (Camera)

• Radionuclide Cystography/ Vesicoureteric reflux study is the technique of choice for the evaluation and follow-up of children with suspected vesicoureteral reflux. It is done in two ways: direct method with direct injection of radiopharmaceuticals in the urinary bladder and indirect method along with DTPA renogram.

• Renal transplant evaluation- radionuclide imaging using 99mTc-DTPA is a useful tool in evaluating medical and surgical complications of renal transplant eg acute tubular necrosis, rejection and surgical mishaps like urinoma, lymphocele, hematoma, ureteral obstruction and vascular complications.

• Testicular Scintigraphy for emergency detection of testicular torsion to save testis.